TRIMETHYLGLYCINE (TMG)
BULK ULTRAFINE GRANULATED
water soluable * dissolves instantly * non-bitter

Commonly known as anhydrous betaine, oxyneurine, this is NOT betaine HCI (hydrochloric acid)

 
 
 
Protect Your Heart, Arteries & Liver...
The newest and most effective natural methylation enhancing compound is TMG. Commonly known as betaine**, glycine betaine, or oxyneurine, TMG is found in most microorganisms and almost all marine and fresh water invertebrates. The best known natural sources of TMG are plants from the chenopodiaceae family, namely, the sugar beet. TMG is often referred to as a quasi-vitamin because although humans and other animals can synthesize it from choline, it can't be synthesized in adequate quantities and generally needs to be included in the diet. TMG is a natural methyl donor, and is one of the phytochemicals recently extruded from plants.
 
Metabolically, TMG is broken down into dimethylglycine (DMG) during the synthesis of the amino acid methionine from homocysteine,the main pathway for the degradation of TMG. A diet high in broccoli, spinach or beets can provide as much as a fifth or even a quarter teaspoon of TMG, just over 500 mg. In the process of extracting pure TMG from sugar beets (a process which does not use any solvents or alcohol called chromatographic separation--the best method), separates betaine based on its physical and chemical properties. There is a residue from extraction from other parts of beets. This residual is less than 1% of the resulting TMG, leaving a 99% pure product in its best and most effective form. In its natural form, TMG is a white crystal with a distinctive mildly sweet taste and aftertaste. TMG may be dissolved into juice, water or tea.
 
Several companies have mistakenly labeled betaine HCL as TMG. If found in capsules, open the capsule and taste the ingredients. If it is strongly acidic it is most likely betaine HCL or hydrochloric acid. Similarly, chewing a tablet should not burn your tongue but have a mild sweet taste.
 
A LITTLE KNOWN SECRET NO LONGER . . .
TMG is not unknown to the medical establishment. Used since 1981 in the treatment of homocystinuria, it has recently been approved by the FDA to make the medical claim that it aids in the treatment of homocystinuria. Sold since the early 1980's or prior, TMG is actually a well understood supplement that has no reports of negative side-effects when used in the usual dosages.
In animals, TMG decreases VLDLs, increases muscle mass, decreases fat content. TMG is also known to increase bone density. These effects are poorly understood but well documented. TMG also helps regulate the methylation process, increasing SAM and reducing risk and potential damage from high homocysteine levels in bodily fluids and tissues.
Taken with permission from "Your Life Depends on it ! Understanding Homocysteine Methylation and Your Health", Paul Frankel, Ph.D., published with Speciality Laboratories, Santa Monica, CA.
The biological benefits of TMG (Trimethyl-glycine)
  • Betaine TMG (not to be confused with Betaine HCL) works along with Vitamin B6, folic acid and Vitamin B12 to augment the formation of SAMe, an amino acid in the brain. Amino acids are proteins.
  • What are some of the benefits of TMG?
  • TMG (Betaine Anhydrous) is a methyl donor with the following applications in human nutrition:
  • Anti-depression: By raising level of beneficial SAM (S-Adenosyl-Methionine). Dose range: 500-1,500 mg daily
  • Body building: In the animal husbandry field, TMG is used to decrease fat and increase meat yield. While human studies have just started, a 200 pound individual with 20% body fat can expect to lose as much as 5 pounds of fat and gain as much as 12 pounds of muscle. Dose range: 500-2,000 mg daily
  • Cardiac protection: Conversion of homocysteine to Methionine. Dose range: 500-1,000 mg daily
  • General Health Preventative: As part of a formula for maintaining good health or disease prevention. Dose range: 500-1,000 mg daily
  • Glutathione Elevation: In several different studies, TMG has been shown to increase hepatic Glutathione, the body's most important antioxidant. Dose range: 500-1,500 mg daily
  • Homocysteine Lowering: Specific for that purpose. The supplement of choice for lowering homocystenuria, Dose range: 500-1,000 mg daily. As used by clinicians and hospitals with patient monitoring -up to 3 grams daily
  • Liver Disorders: As a part of liver-healing and protection formulas. Increases SAM levels in the liver, enables the liver to metabolize fat and protect against many challenges such as alcohol induced cirrhosis. TMG will also decrease bilirubin, alkaline phosphotase, and several other liver enzymes related to a large variety of liver disorders. Significant liver benefits have been shown in 20 studies. Dose range: 500-1,500 mg. daily.
  • Longevity Formulations: As a part of a life extension formula. TMG has shown ability to protect interrogate of cellular DNA through methyl donation. Dose range: 500-1,000 mg daily.
  • Methyl Donor Formulations: Along with B12, Folic acid, and Choline. Dose range: 500-1,500 mg. daily.
  • Performance: Due to it's bi-polar nature, helps osmotic pressure in cells. For example it is used in salmon farming to protect fish against the problems of changing salt content. In humans, TMG maintains normal cellular electrolyte concentrations despite water and electrolyte losses during exercise. TMG also helps metabolize fats, which allows the body to burn fat rather than protein or muscle during exercise. The result is less cramping, increased endurance, and better utilization of fat stores, Dose range: 1,000-2,000 mg daily.
    • IMPORTANT BUYING TIPS:     TMG is very hydroscopic--it absorbs water from the atmosphere and tends to split capsules from expansion which is why many companies tablet it. This characteristic also makes it very heavy and so shipping costs are rather high and many aren't willing to pay them since they can actually cost more than the raw material. Due to our warehouse volume, we don't pass any shipping costs to our customers built into the product which is why our price per gram is the lowest anywhere in the retail sector.
    The average price per gram (1000 mg) on the internet we have found is around .14 to .17 ¢ per gram. Most of these products are tableted products and some claims 1000 mg. per tablet but tablets require fillers to hold the together in the machines, so in truth you could actually be only getting 700 mg. per tablet of active ingredient. The best way to find out is use a scale which measures grams and weigh a tablet...if it is 1 gram, then you know your NOT getting 1 gram of pure TMG since the gram size is in reference to the ¨total¨tablet size, not necessarily the amount of TMG per tab.
    We buy in huge quantities and have an excellent contract with a direct manufacturer so we sell ours by the pound or kilo in its purest form, not by tablets or 50 gram jars. To give a point of reference, a standard kitchen level teaspoon is about 4 grams...so 50 grams is aboout 10-12 teaspoons...not very much !
    OUR INTEGRATIVE MEDICAL CLINIC IN TIJUANA HAS THE FOLLOWING PROTOCOL FOR OUR PATIENTS:
    ACUTE USE (Cardiovascular disease, Diabetes, Stroke, TIA, Syndrome-XYZ, Cancer, Fibromyalgia, etc.): 3-5 GRAMS per day or as directed by docs.
    MAINTENANCE: 1-3 grams per day, or as directed by docs
    SPLIT DOSES UP INTO 2 OR 3 TO KEEP BLOOD LEVELS MORE CONSISTENT

      *Mandatory FDA Disclaimer: The product statements & products shown on this website have not been evaluated by the US Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Those seeking treatment for a specific disease should consult a qualified physician prior to using our products.

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